First Trust Health Care AlphaDEX® Fund (FXH)
Holdings of the Fund as of 11/22/2024

Total Number of Holdings (excluding cash): 77

Security Name Identifier CUSIP Classification Shares / Quantity Market Value Weighting Descending sort
Natera, Inc. NTRA 632307104 Medical Equipment and Services 208,592 $34,889,097.92 3.00%
Premier, Inc. (Class A) PINC 74051N102 Health Care Providers 1,324,043 $30,241,142.12 2.60%
Jazz Pharmaceuticals Plc JAZZ G50871105 Pharmaceuticals and Biotechnology 237,688 $30,107,938.96 2.59%
Insulet Corporation PODD 45784P101 Medical Equipment and Services 113,773 $29,914,334.89 2.57%
Doximity, Inc. (Class A) DOCS 26622P107 Health Care Providers 607,777 $29,294,851.40 2.52%
Roivant Sciences Ltd. ROIV G76279101 Pharmaceuticals and Biotechnology 2,294,701 $28,752,603.53 2.47%
United Therapeutics Corporation UTHR 91307C102 Pharmaceuticals and Biotechnology 73,896 $27,555,079.44 2.37%
Exelixis, Inc. EXEL 30161Q104 Pharmaceuticals and Biotechnology 765,343 $27,253,864.23 2.35%
DaVita Inc. DVA 23918K108 Health Care Providers 161,537 $26,735,988.87 2.30%
ResMed Inc. RMD 761152107 Medical Equipment and Services 108,474 $26,443,791.72 2.28%
Alnylam Pharmaceuticals, Inc. ALNY 02043Q107 Pharmaceuticals and Biotechnology 96,284 $23,578,988.76 2.03%
Tenet Healthcare Corporation THC 88033G407 Health Care Providers 159,330 $22,884,567.90 1.97%
Universal Health Services, Inc. (Class B) UHS 913903100 Health Care Providers 115,633 $22,888,396.02 1.97%
Viatris Inc. VTRS 92556V106 Pharmaceuticals and Biotechnology 1,710,649 $22,871,377.13 1.97%
Ultragenyx Pharmaceutical Inc. RARE 90400D108 Pharmaceuticals and Biotechnology 476,702 $22,519,402.48 1.94%
Intuitive Surgical, Inc. ISRG 46120E602 Medical Equipment and Services 40,427 $22,148,740.49 1.91%
Cardinal Health, Inc. CAH 14149Y108 Pharmaceuticals and Biotechnology 179,701 $21,894,769.84 1.88%
Centene Corporation CNC 15135B101 Health Care Providers 351,765 $21,236,053.05 1.83%
HCA Healthcare, Inc. HCA 40412C101 Health Care Providers 65,156 $21,171,139.08 1.82%
Quest Diagnostics Incorporated DGX 74834L100 Medical Equipment and Services 127,927 $20,927,577.93 1.80%
Zimmer Biomet Holdings, Inc. ZBH 98956P102 Medical Equipment and Services 183,980 $20,278,275.60 1.74%
UnitedHealth Group Incorporated UNH 91324P102 Health Care Providers 33,969 $20,071,263.03 1.73%
Charles River Laboratories International, Inc. CRL 159864107 Pharmaceuticals and Biotechnology 100,830 $19,739,489.10 1.70%
The Cigna Group CI 125523100 Health Care Providers 57,329 $18,829,710.05 1.62%
Humana Inc. HUM 444859102 Health Care Providers 62,703 $18,692,391.33 1.61%
Intra-Cellular Therapies, Inc. ITCI 46116X101 Pharmaceuticals and Biotechnology 217,146 $18,607,240.74 1.60%
Royalty Pharma Plc (Class A) RPRX G7709Q104 Pharmaceuticals and Biotechnology 702,038 $18,554,864.34 1.60%
GE HealthCare Technologies Inc. GEHC 36266G107 Medical Equipment and Services 211,621 $17,446,035.24 1.50%
Enovis Corp. ENOV 194014502 Medical Equipment and Services 369,071 $17,224,543.57 1.48%
Incyte Corporation INCY 45337C102 Pharmaceuticals and Biotechnology 240,370 $17,239,336.40 1.48%
Edwards Lifesciences Corporation EW 28176E108 Medical Equipment and Services 240,771 $16,969,540.08 1.46%
Perrigo Company Plc PRGO G97822103 Pharmaceuticals and Biotechnology 605,739 $17,003,093.73 1.46%
Molina Healthcare, Inc. MOH 60855R100 Health Care Providers 57,640 $16,761,135.60 1.44%
Encompass Health Corporation EHC 29261A100 Health Care Providers 164,408 $16,624,936.96 1.43%
Henry Schein, Inc. HSIC 806407102 Medical Equipment and Services 217,949 $16,363,610.92 1.41%
Biogen Inc. BIIB 09062X103 Pharmaceuticals and Biotechnology 102,460 $16,178,434.00 1.39%
Organon & Co. OGN 68622V106 Pharmaceuticals and Biotechnology 1,038,194 $15,863,604.32 1.36%
Hologic, Inc. HOLX 436440101 Medical Equipment and Services 195,047 $15,402,861.59 1.33%
Elevance Health Inc. ELV 036752103 Health Care Providers 38,194 $15,374,994.70 1.32%
Johnson & Johnson JNJ 478160104 Pharmaceuticals and Biotechnology 98,042 $15,213,177.14 1.31%
Medtronic Plc MDT G5960L103 Medical Equipment and Services 176,481 $15,214,427.01 1.31%
Chemed Corporation CHE 16359R103 Health Care Providers 26,438 $15,095,040.48 1.30%
Inspire Medical Systems, Inc. INSP 457730109 Medical Equipment and Services 75,283 $14,208,160.59 1.22%
Eli Lilly and Company LLY 532457108 Pharmaceuticals and Biotechnology 17,933 $13,414,063.33 1.15%
Exact Sciences Corporation EXAS 30063P105 Pharmaceuticals and Biotechnology 233,244 $12,340,940.04 1.06%
Regeneron Pharmaceuticals, Inc. REGN 75886F107 Pharmaceuticals and Biotechnology 15,114 $11,154,132.00 0.96%
Labcorp Holdings Inc. LH 504922105 Medical Equipment and Services 44,434 $10,649,496.78 0.92%
Stryker Corporation SYK 863667101 Medical Equipment and Services 27,487 $10,578,371.95 0.91%
West Pharmaceutical Services, Inc. WST 955306105 Medical Equipment and Services 33,083 $10,473,746.97 0.90%
Waters Corporation WAT 941848103 Medical Equipment and Services 27,593 $10,305,157.71 0.89%
Abbott Laboratories ABT 002824100 Medical Equipment and Services 87,100 $10,256,896.00 0.88%
Vertex Pharmaceuticals Incorporated VRTX 92532F100 Pharmaceuticals and Biotechnology 21,351 $9,628,660.47 0.83%
Amedisys, Inc. AMED 023436108 Health Care Providers 102,895 $9,326,402.80 0.80%
Becton, Dickinson and Company BDX 075887109 Medical Equipment and Services 41,188 $9,226,112.00 0.79%
Amgen Inc. AMGN 031162100 Pharmaceuticals and Biotechnology 30,820 $9,077,414.60 0.78%
AbbVie Inc. ABBV 00287Y109 Pharmaceuticals and Biotechnology 50,286 $8,898,107.70 0.77%
Agilent Technologies, Inc. A 00846U101 Medical Equipment and Services 66,881 $8,951,353.04 0.77%
Zoetis Inc. ZTS 98978V103 Pharmaceuticals and Biotechnology 50,825 $8,993,992.00 0.77%
IQVIA Holdings Inc. IQV 46266C105 Health Care Providers 41,905 $8,457,267.10 0.73%
Bruker Corporation BRKR 116794108 Medical Equipment and Services 143,793 $8,206,266.51 0.71%
Thermo Fisher Scientific Inc. TMO 883556102 Medical Equipment and Services 16,053 $8,239,362.78 0.71%
Teleflex Incorporated TFX 879369106 Medical Equipment and Services 40,152 $7,697,539.92 0.66%
Masimo Corporation MASI 574795100 Medical Equipment and Services 37,239 $6,440,857.44 0.55%
Penumbra, Inc. PEN 70975L107 Medical Equipment and Services 25,552 $6,256,151.68 0.54%
Veeva Systems Inc. (Class A) VEEV 922475108 Health Care Providers 23,657 $5,123,633.06 0.44%
Medpace Holdings, Inc. MEDP 58506Q109 Pharmaceuticals and Biotechnology 14,875 $5,024,031.25 0.43%
BioMarin Pharmaceutical Inc. BMRN 09061G101 Pharmaceuticals and Biotechnology 70,639 $4,539,262.14 0.39%
The Cooper Companies, Inc. COO 216648501 Medical Equipment and Services 44,999 $4,535,899.20 0.39%
Align Technology, Inc. ALGN 016255101 Medical Equipment and Services 19,524 $4,410,276.36 0.38%
Bio-Techne Corporation TECH 09073M104 Medical Equipment and Services 62,119 $4,427,842.32 0.38%
Steris Plc STE G8473T100 Medical Equipment and Services 20,471 $4,387,754.14 0.38%
Baxter International Inc. BAX 071813109 Medical Equipment and Services 130,765 $4,342,705.65 0.37%
Revvity, Inc. RVTY 714046109 Medical Equipment and Services 38,867 $4,354,270.01 0.37%
Danaher Corporation DHR 235851102 Medical Equipment and Services 17,859 $4,211,866.56 0.36%
Avantor, Inc. AVTR 05352A100 Medical Equipment and Services 191,928 $3,988,263.84 0.34%
DENTSPLY SIRONA Inc. XRAY 24906P109 Medical Equipment and Services 183,486 $3,444,032.22 0.30%
10X Genomics, Inc. (Class A) TXG 88025U109 Pharmaceuticals and Biotechnology 219,892 $3,146,654.52 0.27%
US Dollar $USD Other 1,432,848 $1,432,848.34 0.12%
Holdings are subject to change.

The holdings information set forth above for the date indicated reflects creation and redemption transactions from the prior business day and may differ from the holdings information currently available from the Fund's custodian and accounting agent. With respect to the market value of the Fund's holdings set forth above, the pricing sources are generally third party vendors. The Fund ultimately relies on pricing information provided by the Fund's accounting agent.