Dow Jones Global Titans Portfolio, Series 46

In recent years, globalization has become a reality. The once distinct geographic, economic and cultural lines have not only been blurred, but nearly erased. With this transformation, we have seen the emergence of a new breed of mega-corporations–the Global Titans^®.

The Dow Jones Global Titans Portfolio invests in 50 of the world’s largest and most-established blue-chip companies included in the Dow Jones Global Titans 50^TM Index. The portfolio provides exposure to companies headquartered in countries around the world, aiming to reduce risk through country diversification.

Global Diversification

Global diversification is considered one of the best ways of reducing risk by decreasing dependency on the performance of a single economy. Because large multinational corporations frequently have operations in multiple countries and generate revenues worldwide, they typically have a buffer against regional economic downturns that other smaller and more centralized companies may not have. It is important to note that diversification does not guarantee a profit or protect against loss.

Characteristics of Global Titans^®

Market Leadership

• To be identified as Global Titans^®, the companies must be well established and have a broad client base.


• They must be well known to global investors for either their long history of success or offer widely used products or services.


• They must be market leaders in their industry with either a dominant position or a competitive advantage.


• They must be among the largest of blue-chip companies in the global arena.

Multinational Exposure

• All companies must be market and industry leaders globally, rather than just at the local level.


• All companies must have international market exposure, either selling or providing services, outside of their home markets.

Portfolio Objective

This unit investment trust seeks above-average capital appreciation; however, there is no assurance the objective will be met.

The portfolio is invested in companies included in the Dow Jones Global Titans 50^TM Index as of the business day prior to the portfolio's initial date of deposit. However, it will not be adjusted to reflect changes to the components of the Index, if any, during the life of the portfolio.

You should consider the portfolio's investment objective, risks, and charges and expenses carefully before investing. Contact your financial professional or call First Trust Portfolios, L.P. at 1.800.621.1675 to request a prospectus, which contains this and other information about the portfolio. Read it carefully before you invest.

Risk Considerations
An investment in this unmanaged unit investment trust should be made with an understanding of the risks involved with owning common stocks, such as an economic recession and the possible deterioration of either the financial condition of the issuers of the equity securities or the general condition of the stock market.

You should be aware that the portfolio is concentrated in stocks in the information technology sector which involves additional risks, including limited diversification. The companies engaged in the information technology sector are subject to fierce competition, high research and development costs, and their products and services may be subject to rapid obsolescence. Technology company stocks, especially those which are Internet-related, may experience extreme price and volume fluctuations that are often unrelated to their operating performance.

Securities of non-U.S. issuers are subject to additional risks, including currency fluctuations, political risks, withholding, the lack of adequate financial information, and exchange control restrictions impacting non-U.S. issuers.

Large capitalization companies may grow at a slower rate than the overall market.

As the use of Internet technology has become more prevalent in the course of business, the trust has become more susceptible to potential operational risks through breaches in cybersecurity.

Ongoing armed conflicts between Russia and Ukraine in Europe and among Israel, Hamas and other militant groups in the Middle East have caused and could continue to cause significant market disruptions and volatility within the markets in Russia, Europe, the Middle East and the United States. The hostilities and sanctions resulting from those hostilities could have a significant impact on certain investments as well as performance.

The ongoing effects of the COVID-19 global pandemic, or the potential impacts of any future public health crisis, may cause significant volatility and uncertainty in global financial markets. While vaccines have been developed, there is no guarantee that vaccines will be effective against future variants of the disease.

The value of the securities held by the trust may be subject to steep declines or increased volatility due to changes in performance or perception of the issuers.

This UIT is a buy and hold strategy and investors should consider their ability to hold the trust until maturity. There may be tax consequences unless units are purchased in an IRA or other qualified plan.

The Dow Jones Global Titans 50^TM Index is a product of S&P Dow Jones Indices LLC or its affiliates (“SPDJI”) and has been licensed for use by First Trust Portfolios L.P. Standard & Poor’s^® and S&P^® are registered trademarks of Standard & Poor’s Financial Services LLC (“S&P”); Dow Jones® is a registered trademark of Dow Jones Trademark Holdings LLC (“Dow Jones”); and these trademarks have been licensed for use by SPDJI and sublicensed for certain purposes by First Trust Portfolios L.P. The Dow Jones Global Titans Portfolio is not sponsored, endorsed, sold or promoted by SPDJI, Dow Jones, S&P, their respective affiliates, and none of such parties make any representation regarding the advisability of investing in such product nor do they have any liability for any errors, omissions, or interruptions of the Dow Jones Global Titans 50^TM Index.